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High CMRR Instrumentation Amplifier (Schematic and Layout) design for biomedical applications

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Instrumentation amplifiers are intended to be used whenever acquisition of a useful signal is difficult. IA’s must have extremely high input impedances because source impedances may be high and/or unbalanced. bias and offset currents are low and relatively stable so that the source impedance need not be constant. Balanced differential inputs are provided so that the signal source may be referenced to any reasonable level independent of the IA output load reference. Common mode rejection, a measure of input balance, is very high so that noise pickup and ground drops, characteristic of remote sensor applications, are minimized.Care is taken to provide high, well characterized stability of critical parameters under varying conditions, such as changing temperatures and supply voltages. Finally, all components that are critical to the performance of the IA are internal to the device. The precision of an IA is provided at the expense of flexibility. By committing to the one specific task of
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Low Frequency Sinewave Generators

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The two circuits below illustrate generating low frequency sinewaves by shifting the phase of the signal through an RC network so that oscillation occurs where the total phase shift is 360 degrees. The transistor circuit on the right produces a reasonable sinewave at the collector of the 3904 which is buffered by the JFET to yield a low impedance output. The circuit gain is critical for low distortion and you may need to adjust the 500 ohm resistor to achieve a stable waveform with minimum distortion. The transistor circuit is not recommended for practical applications due to the critical adjustments needed.

The op-amp based phase shift oscillator is much more stable than the single transistor version since the gain can be set higher than needed to sustain oscillation and the output is taken from the RC network which filters out most of the harmonic distortion. The sinewave output from the RC network is buffered and the amplitude restored by the second (top) op-amp which has gain of around 28dB. Frequency is around 600 Hz for RC values shown (7.5K and 0.1uF) and can be reduced by proportionally increasing the network resistors (7.5K). The 7.5K value at pin 2 of the op-amp controls the oscillator circuit gain and is selected so that the output at pin 1 is slightly clipped at the positive and negative peaks. The sinewave output at pin 7 is about 5 volts p-p using a 12 volt supply and appears very clean on a scope since the RC network filters out most all distortion occurring at pin 1. 
 

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